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In the context of hematopoiesis, what does the term 'myeloid' refer to?
All lymphocytes
Any leukocyte that is not a lymphocyte
Bone marrow only
B cells specifically
The correct answer is: Any leukocyte that is not a lymphocyte
The term 'myeloid' is used in the context of hematopoiesis to refer to any leukocyte that is not a lymphocyte. This includes various types of white blood cells such as neutrophils, eosinophils, basophils, monocytes, and macrophages, all of which derive from the myeloid lineage. These cells originate from multipotent hematopoietic stem cells in the bone marrow, where they undergo differentiation. The usage of 'myeloid' distinguishes these cells from lymphocytes, which are part of a different lineage (the lymphoid lineage) and include T cells and B cells. Understanding this distinction is crucial for recognizing how different blood cell types are formed and their distinct roles in the immune response and other physiological functions. This knowledge underpins much of the pathophysiology associated with various hematologic conditions, including leukemias and other blood disorders that may arise from abnormalities in myeloid or lymphoid lineage cells.